Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.37 |
| ▸ | MPL | P40238 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19488554 | 0.89 | SCN10A (0.40) | SCN10AAAK1CACNA1BROCK2MELK | |
| SCHEMBL19488473 | 0.85 | SCN10A (0.39) | SCN10AAAK1ROCK2MELK | |
| SCHEMBL19488290 | 0.84 | SCN10A (0.37) | SCN10AAAK1CACNA1BROCK2MELK | |
| SCHEMBL10200269 | 0.84 | SCN10A (0.52) | SCN10AAAK1MPLNPC1RAB9A | |
| SCHEMBL19488471 | 0.82 | SCN10A (0.40) | SCN10AAAK1 | |
| SCHEMBL19488498 | 0.79 | SCN10A (0.42) | SCN10AAAK1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL19488583 | 0.79 | SCN10A (0.39) | SCN10AAAK1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL19488295 | 0.78 | AAK1 (0.37) | SCN10AAAK1 | |
| SCHEMBL19488293 | 0.78 | AAK1 (0.37) | SCN10AAAK1 | |
| SCHEMBL19488296 | 0.78 | SCN10A (0.43) | SCN10AAAK1CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |