Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MELK | Q14680 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 4/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.30 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.30 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.30 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19488473 | 0.94 | SCN10A (0.39) | SCN10AAAK1ROCK2MELKSSTR3 | |
| SCHEMBL19488306 | 0.89 | SCN10A (0.39) | SCN10AAAK1ROCK2MELKCACNA1B | |
| SCHEMBL19488293 | 0.89 | AAK1 (0.37) | SCN10AAAK1 | |
| SCHEMBL19488295 | 0.89 | AAK1 (0.37) | SCN10AAAK1SSTR3 | |
| SCHEMBL19488290 | 0.87 | SCN10A (0.37) | SCN10AAAK1ROCK2MELKCACNA1B | |
| SCHEMBL11982065 | 0.86 | SSTR3 (0.36) | SCN10ASSTR3SSTR4SSTR5MAPK13 | |
| SCHEMBL20221011 | 0.86 | SSTR3 (0.36) | SCN10ASSTR3SSTR4SSTR5MAPK13 | |
| SCHEMBL19488471 | 0.84 | SCN10A (0.40) | SCN10AAAK1HRH4HRH3 | |
| SCHEMBL19339890 | 0.82 | NR1H4 (0.34) | SCN10ASSTR3MAPK13MAPK12MAPK11 | |
| SCHEMBL13192596 | 0.81 | SCN10A (0.56) | SCN10AAAK1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |