Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 5/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19488471 | 0.95 | SCN10A (0.40) | SCN10AAAK1ABL1HRH4HRH3 | |
| SCHEMBL19488473 | 0.85 | SCN10A (0.39) | SCN10AAAK1ABL1HRH4HRH3 | |
| SCHEMBL10202369 | 0.82 | SCN10A (0.54) | SCN10AAAK1USP30PARP1 | |
| SCHEMBL19488554 | 0.81 | SCN10A (0.40) | SCN10AAAK1HRH4HRH3 | |
| SCHEMBL13087366 | 0.80 | SCN10A (0.31) | SCN10A | |
| SCHEMBL19488296 | 0.79 | SCN10A (0.43) | SCN10AAAK1PARP1CSNK2A2CSNK2B | |
| SCHEMBL19488306 | 0.79 | SCN10A (0.39) | SCN10AAAK1LMNACSNK2A2CSNK2B | |
| SCHEMBL19488498 | 0.78 | SCN10A (0.42) | SCN10AAAK1USP30PARP1CSNK2A2 | |
| SCHEMBL19488291 | 0.77 | SCN10A (0.41) | SCN10AAAK1 | |
| SCHEMBL19488771 | 0.77 | SCN10A (0.41) | SCN10AAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |