Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19488605 | 0.82 | PDE10A (0.35) | AAK1SMN1; SMN2 | |
| SCHEMBL18526605 | 0.80 | SSTR4 (0.33) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL18526689 | 0.80 | HDAC1 (0.36) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL20055131 | 0.78 | LMNA (0.33) | AAK1SMN1; SMN2HDAC1HDAC3 | |
| SCHEMBL12648045 | 0.78 | SSTR4 (0.39) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL18526454 | 0.77 | GABRA1 (0.37) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL19488576 | 0.77 | SSTR4 (0.37) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL19488582 | 0.77 | AAK1 (0.32) | AAK1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL19339742 | 0.76 | GABRA1 (0.39) | AAK1SMN1; SMN2GABRA1GABRG2GABRB3 | |
| SCHEMBL19339763 | 0.74 | SSTR4 (0.41) | SMN1; SMN2HDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |