Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19488649 | 0.91 | MAPT (0.33) | MAPTTP53KDM4EALDH1A1THRB | |
| SCHEMBL19488879 | 0.90 | MAPT (0.33) | MAPTTP53KDM4EALDH1A1THRB | |
| SCHEMBL19488857 | 0.89 | MAPT (0.34) | MAPTTP53KDM4EALDH1A1THRB | |
| SCHEMBL19488652 | 0.84 | KDM4E (0.38) | MAPTTP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19488325 | 0.76 | MAPT (0.34) | MAPTTP53KDM4EALDH1A1THRB | |
| SCHEMBL19488877 | 0.74 | — | — | |
| SCHEMBL19488884 | 0.73 | ALDH1A1 (0.39) | MAPTTP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19488545 | 0.73 | DHODH (0.36) | MAPTTP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19488335 | 0.72 | DHODH (0.32) | MAPTTP53KDM4ETHRBSMN1; SMN2 | |
| SCHEMBL19488331 | 0.71 | KDM4E (0.33) | MAPTTP53KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |