Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.70 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.68 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.66 |
| ▸ | F2 | P00734 | 3/20 | 0.66 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.66 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.66 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.66 |
| ▸ | PLAU | P00749 | 1/20 | 0.66 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.66 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.66 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.66 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.66 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.66 |
| ▸ | F10 | P00742 | 1/20 | 0.66 |
| ▸ | PLG | P00747 | 1/20 | 0.66 |
| ▸ | S100B | P04271 | 1/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.66 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12348319 | 0.83 | PRSS1 (0.76) | PRSS1TMPRSS2PRMT1F2ST14 | |
| Propamidine SCHEMBL231060 | 0.81 | TMPRSS2 (1.00) | PRSS1TMPRSS2PRMT1F2ST14 | |
| Hydrochloric Acid SCHEMBL11783188 | 0.81 | PRSS1 (1.00) | PRSS1TMPRSS2PRMT1F2ST14 | |
| Hydrochloric Acid SCHEMBL11784186 | 0.81 | PRSS1 (0.77) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL6408670 | 0.81 | PRSS1 (1.00) | PRSS1TMPRSS2PRMT1F2ST14 | |
| Heptamidine SCHEMBL14599630 | 0.79 | PRMT1 (1.00) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL13462623 | 0.79 | PARP10 (0.66) | — | |
| SCHEMBL428950 | 0.79 | PRSS1 (1.00) | PRSS1TMPRSS2PRMT1F2ST14 | |
| Propamidine SCHEMBL2689252 | 0.79 | PRSS1 (1.00) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL1715535 | 0.79 | PRSS1 (0.70) | PRSS1TMPRSS2PRMT1F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017180794-A1 | DEUTERATED O-SULFATED BETA-LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA-LACTAMS | SKYLINE ANTIINFECTIVES, INC. (US) | 2017-10-19 | — | — | WO | disclosed |