Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | CCKBR | P32239 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775909 | 0.86 | GPR84 (0.58) | GPR84SLC6A4HTR2APCSK9HTR1A | |
| SCHEMBL27929625 | 0.78 | GPR84 (1.00) | GPR84SLC6A4HTR2ATRPM8CSNK2A1 | |
| SCHEMBL31744805 | 0.78 | GPR84 (0.73) | GPR84SLC6A4HTR2ATRPM8CSNK2A1 | |
| SCHEMBL31744667 | 0.77 | GPR84 (0.83) | GPR84SLC6A4HTR2ATRPM8CSNK2A1 | |
| SCHEMBL31744782 | 0.77 | GPR84 (0.71) | GPR84SLC6A4HTR2ATRPM8CSNK2A1 | |
| SCHEMBL31744810 | 0.74 | GPR84 (0.78) | GPR84SLC6A4HTR2ATRPM8CSNK2A1 | |
| SCHEMBL31744842 | 0.73 | GPR84 (0.76) | GPR84SLC6A4HTR2ATRPM8CSNK2A1 | |
| SCHEMBL31744779 | 0.73 | GPR84 (0.57) | GPR84SLC6A4HTR2ATRPM8CSNK2A1 | |
| SCHEMBL28547448 | 0.73 | GPR84 (0.75) | GPR84SLC6A4HTR2ATRPM8CSNK2A1 | |
| SCHEMBL31744792 | 0.73 | GPR84 (0.65) | GPR84SLC6A4HTR2ATRPM8CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795600-B2 | Method for treating abnormal β-amyloid mediated diseases | NATIONAL TAIWAN NORMAL UNIVERSITY (TW) | 2017-10-24 | — | — | US | disclosed |