SCHEMBL31744792

SCHEMBL31744792

Brc1ccc2[nH]cc(Cc3ccc4ccccc4c3)c2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.65
HTR2A P28223 2/20 0.51
TRPM8 Q7Z2W7 1/20 0.51
CSNK2A1 P68400 1/20 0.50
LTA4H P09960 1/20 0.49
PLA2G2A P14555 1/20 0.49
MC5R P33032 1/20 0.48
MC3R P41968 1/20 0.48
MC1R Q01726 1/20 0.48
HTR1A P08908 3/20 0.46
SLC6A4 P31645 3/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HTR6 P50406 2/20 0.44
AHR P35869 1/20 0.43
CYP2A6 P11509 1/20 0.43
PCSK9 Q8NBP7 2/20 0.43
ADRA2A P08913 1/20 0.43
DRD2 P14416 1/20 0.43
ADRA2B P18089 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28547448 0.84 GPR84 (0.75) GPR84HTR2ATRPM8CSNK2A1HTR1A
SCHEMBL31744785 0.84 GPR84 (0.80) GPR84HTR2ATRPM8CSNK2A1HTR1A
SCHEMBL31744847 0.82 GPR84 (0.73) GPR84HTR2ATRPM8CSNK2A1HTR1A
SCHEMBL31744844 0.82 GPR84 (0.67) GPR84HTR2ATRPM8CSNK2A1LTA4H
SCHEMBL27929625 0.80 GPR84 (1.00) GPR84HTR2ATRPM8CSNK2A1HTR1A
SCHEMBL31744667 0.79 GPR84 (0.83) GPR84HTR2ATRPM8CSNK2A1HTR1A
SCHEMBL31744782 0.79 GPR84 (0.71) GPR84HTR2ATRPM8CSNK2A1LTA4H
SCHEMBL31744931 0.79 GPR84 (0.67) GPR84HTR2ATRPM8CSNK2A1HTR1A
SCHEMBL31744584 0.78 GPR84 (0.71) GPR84HTR2ATRPM8CSNK2A1HTR1A
SCHEMBL31744639 0.78 GPR84 (0.71) GPR84HTR2ATRPM8CSNK2A1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US claimed
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US disclosed
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 GPR84 4183/4885HTR2A 4846/4885TRPM8 2757/4885
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 GPR84 4183/4885HTR2A 4846/4885TRPM8 2757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.