Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19676040 | 0.77 | LMNA (0.43) | LMNAL3MBTL1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10613679 | 0.77 | GAA (0.50) | LMNAL3MBTL1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10613674 | 0.77 | GAA (0.50) | LMNAL3MBTL1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL16471892 | 0.75 | NR4A1 (0.45) | LMNAL3MBTL1ALDH1A1G6PC1MEN1 | |
| SCHEMBL631266 | 0.74 | L3MBTL1 (0.40) | LMNAL3MBTL1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL631267 | 0.74 | L3MBTL1 (0.40) | LMNAL3MBTL1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL19676090 | 0.74 | LMNA (0.40) | LMNAL3MBTL1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL4024136 | 0.73 | LMNA (0.52) | LMNAL3MBTL1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL12593473 | 0.73 | LMNA (0.52) | LMNAL3MBTL1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3258201 | 0.73 | LMNA (0.52) | LMNAL3MBTL1ALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796753-B2 | N-substituted indenoisoquinolines and syntheses thereof | PURDUE RESEARCH FOUNDATION (US) | 2017-10-24 | — | — | US | disclosed |