Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MPI | P34949 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19490686 | 0.88 | MAPT (0.56) | DHODHMAPTALDH1A1POLBKMT2A | |
| SCHEMBL19490651 | 0.87 | DHODH (0.57) | DHODHMAPTALDH1A1POLBKMT2A | |
| SCHEMBL19490684 | 0.84 | MAPT (0.54) | DHODHMAPTALDH1A1POLBKMT2A | |
| SCHEMBL19490831 | 0.79 | CA12 (0.52) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL19490683 | 0.78 | PTGS2 (0.48) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL19490832 | 0.78 | MAPT (0.47) | DHODHMAPTALDH1A1POLBKMT2A | |
| SCHEMBL3365283 | 0.77 | DHODH (0.78) | DHODHMAPTALDH1A1POLBKMT2A | |
| SCHEMBL802038 | 0.77 | DHODH (0.78) | DHODHMAPTALDH1A1POLBKMT2A | |
| SCHEMBL3369761 | 0.76 | DHODH (0.76) | DHODHMAPTALDH1A1POLBKMT2A | |
| SCHEMBL3369764 | 0.76 | DHODH (0.76) | DHODHMAPTALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796684-B2 | Materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |