Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MPI | P34949 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19490832 | 0.89 | MAPT (0.47) | MAPTALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL19490831 | 0.88 | CA12 (0.52) | MAPTALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL19490686 | 0.84 | MAPT (0.56) | MAPTALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL19490647 | 0.84 | DHODH (0.56) | MAPTALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL18632804 | 0.80 | CA12 (0.41) | MAPTALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL11413951 | 0.77 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL19490683 | 0.77 | PTGS2 (0.48) | MAPTALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL19490692 | 0.76 | SMN1; SMN2 (0.63) | MAPTALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL19490943 | 0.75 | SIRT2 (0.46) | MAPTALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL12566830 | 0.74 | MAPT (0.78) | MAPTALDH1A1KDM4EL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796684-B2 | Materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |