SCHEMBL194918

SCHEMBL194918

COc1ccc([C]=S)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA12 O43570 1/20 0.58
CA14 Q9ULX7 1/20 0.58
APP P05067 3/20 0.52
ACHE P22303 1/20 0.48
MIF P14174 2/20 0.47
TDP1 Q9NUW8 3/20 0.46
MAPK1 P28482 2/20 0.46
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4082593 0.83 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL10300057 0.78 APP (0.77) CA1CA2CA7CA9CA12
SCHEMBL674764 0.78 APP (0.77) CA1CA2CA7CA9CA12
SCHEMBL10863333 0.76 APP (0.32) APP
1,4-Dimethoxybenzene SCHEMBL21802643 0.76 CA1 (1.00) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.76 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL497836 0.76 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL9715639 0.76 APP (0.74) CA1CA2CA7CA9CA12
SCHEMBL16741894 0.75 CA4 (0.59) CA1CA2CA7CA9CA12
SCHEMBL187127 0.74 CA1 (0.58) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006539-A Thromborane inhibitor NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1991-04-09 US claimed
EP-3042934-B1 COLORED COMPOSITION, CURED FILM, COLOR FILTER, COLOR-FILTER MANUFACTURING METHOD, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, POLYMER, AND XANTHENE DYE FUJIFILM CORP (JP) 2022-11-09 EP disclosed
EP-2572243-B1 POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2021-04-07 EP disclosed
US-20200096864-A1 FILM, COLOR FILTER, SOLID IMAGE PICKUP ELEMENT, AND INFRARED SENSOR FUJIFILM CORPORATION (JP) 2020-03-26 US disclosed
US-10578966-B2 Coloring composition, film, color filter, pattern forming method, method of manufacturing color filter, solid image pickup element, and infrared sensor FUJIFILM CORPORATION (JP) 2020-03-03 US disclosed
EP-2715416-B1 COLORED RADIATION-SENSITIVE COMPOSITION FOR COLOR FILTER, PATTERN FORMING METHOD, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORP (JP) 2019-10-30 EP disclosed
US-10409158-B2 Coloring composition, cured film, color filter, method for producing color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2019-09-10 US disclosed
EP-2598946-B1 POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2019-04-03 EP disclosed
US-20190094688-A1 XANTHENE DYE FUJIFILM CORPORATION (JP) 2019-03-28 US disclosed
US-10191369-B2 Colored composition, cured film, color filter, color-filter manufacturing method, solid-state imaging element, image display device, polymer, and xanthene dye FUJIFILM CORPORATION (JP) 2019-01-29 US disclosed
EP-1150951-A1 3-SUBSTITUTED PYRROLIDINES USEFUL AS INHIBITORS OF MATRIX METALLO-PROTEINASES Aventis Pharmaceuticals Inc. (US) 2001-11-07 EP disclosed
EP-1140984-A1 SELECTIVE INHIBITORS OF MMP-12 Aventis Pharmaceuticals Inc. (US) 2001-10-10 EP disclosed
EP-1140818-A1 AMIDOMALONAMIDES AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEINASE Aventis Pharmaceuticals Inc. (US) 2001-10-10 EP disclosed
US-6262080-B1 3-(thio-substitutedamido)-lactams useful as inhibitors of matrix metalloproteinase AVANTIS PHARMACEUTICALS INC. 2001-07-17 US disclosed
WO-2000040564-A1 N-CARBOXYMETHYL SUBSTITUTED BENZOLACTAMS AS INHIBITORS OF MATRIX METALLOPROTEINASE AVENTIS PHARMACEUTICALS INC. (US) 2000-07-13 WO disclosed
WO-2000040552-A1 AMIDOMALONAMIDES AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEINASE AVENTIS PHARMACEUTICALS INC. (US) 2000-07-13 WO disclosed
WO-2000040600-A1 SELECTIVE INHIBITORS OF MMP-12 AVENTIS PHARMACEUTICALS INC. (US) 2000-07-13 WO disclosed
WO-2000040578-A1 3-(THIO-SUBSTITUTED AMIDO)-LACTAMS USEFUL AS INHIBITORS OF MATRIX METALLOPROTEINASE AVENTIS PHARMACEUTICALS INC. (US) 2000-07-13 WO disclosed
WO-2000040553-A1 3-SUBSTITUTED PYRROLIDINES USEFUL AS INHIBITORS OF MATRIX METALLO-PROTEINASES AVENTIS PHARMACEUTICALS INC. (US) 2000-07-13 WO disclosed
EP-0103445-A2 Process for production of prostaglandins E or F, and novel 7-(thiocarbo-acyloxy) prostaglandins E or F TEIJIN LIMITED (JP) 1984-03-21 EP disclosed