SCHEMBL187127

SCHEMBL187127

C#Cc1ccc(OC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA12 O43570 1/20 0.58
CA14 Q9ULX7 1/20 0.58
APP P05067 2/20 0.52
ACHE P22303 1/20 0.48
TDP1 Q9NUW8 3/20 0.46
MAPK1 P28482 2/20 0.46
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30998834 0.97 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL30998827 0.97 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL30998823 0.97 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL31403396 0.97 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL709673 0.93 APP (0.63) CA1CA2CA7CA9CA12
SCHEMBL4552830 0.93 LTA4H (0.54) CA1CA2CA7CA9CA12
SCHEMBL6736458 0.91 APP (0.50) CA1CA2CA7CA9CA12
SCHEMBL2601885 0.87 RELA (0.59) ALDH1A1KDM4ENPC1MAPTRAB9A
SCHEMBL10370252 0.87 PKM (0.47) CA1CA2CA7CA9CA12
SCHEMBL10032992 0.87 CA1 (0.44) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2659 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059955-A Imidazo pyridone compound, photocatalysis continuous synthesis method and application thereof 南京工业大学 2026-05-19 CN claimed
CN-122036799-A Gold (I) complex containing alkyne-based ligand, preparation method thereof and application thereof in preparation of antitumor drugs 西南医科大学附属医院 2026-05-15 CN claimed
CN-120132861-A Copper-based high-entropy alloy material and preparation method and application thereof 温州大学新材料与产业技术研究院 2025-06-13 CN claimed
CN-116606310-B Heterogeneous catalyst for catalyzing alkyne and B2Pin2Application in borohydride reaction 昆明理工大学 2025-05-23 CN claimed
CN-119930580-A Alkenyl indole derivative, preparation method thereof and application thereof in RNA fluorescent probe field 广东工业大学 2025-05-06 CN claimed
US-20250122132-A1 NITRIFICATION INHIBITORS LINCOLN UNIVERSITY (NZ) 2025-04-17 US claimed
CN-119771506-A Supported Cu-based nanocluster catalyst and application thereof 安徽大学 2025-04-08 CN claimed
CN-119735535-A Synthesis method and application of electrophilic selenium deuterated methyl reagent 杭州师范大学 2025-04-01 CN claimed
CN-116162122-B Dehydroepiandrosterone triazole derivative and preparation method and application thereof 郑州工程技术学院 2025-03-28 CN claimed
CN-119608153-A Preparation method and hydrogenation application of Pd-Ru synergistic catalyst based on metal organic framework 聊城大学 2025-03-14 CN claimed
EP-0515514-B1 2-ARALKOXY AND 2-ALKOXY ADENOSINE DERIVATIVES AS CORONARY VASODILATORS AND ANTIHYPERTENSIVE AGENTS DISCOVERY THERAPEUTICS INC (US) 2000-08-30 EP claimed
EP-0351856-B1 Thiazolo[5,4-b]azepine compounds TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-09-15 EP claimed
EP-0584223-B1 NOVEL IMMUNOSUPPRESSIVE COMPOUNDS VERTEX PHARMA (US) 1999-08-11 EP claimed
EP-0690855-B1 BENZOPYRANES AS POTASSIUM CHANNEL OPENERS PFIZER LTD (GB) 1996-12-18 EP claimed
EP-0420699-B1 Ferromagnetic member consiting of organic material CANON KK (JP) 1995-11-22 EP claimed
US-5461132-A Organic magnetic member, organic ferromagnetic member, and process for producing the same, and time-responsible organic ferromagnetic member and process for controlling development of ferromagnetism CANON KABUSHIKI KAISHA (JP) 1995-10-24 US claimed
EP-0338852-B1 Process for the carbonylation of arylalkyl halides HOECHST CELANESE CORP (US) 1994-11-30 EP claimed
EP-0607077-A1 Salts of 4-pyrimidinone derivatives, their preparation and their application in therapy SYNTHELABO (FR) 1994-07-20 EP claimed
EP-0500409-A1 4-Pyrimidinone derivatives, their preparation and their application in therapy SYNTHELABO (FR) 1992-08-26 EP claimed
EP-0161841-B1 2-(N-SUBSTITUTEGUANIDINO)-4-HETERO-ARYLTHIAZOLE ANTIULCER AGENTS PFIZER INC. (US) 1989-07-19 EP claimed