Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19492781 | 0.85 | CHRM2 (0.37) | MAPTTHRBKDM4EALDH1A1TSHR | |
| SCHEMBL19492642 | 0.84 | PDE2A (0.34) | MAPT | |
| SCHEMBL20768158 | 0.82 | PDE2A (0.48) | MAPTTHRBHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL31171093 | 0.82 | PDE2A (0.48) | MAPTTHRBHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL20768156 | 0.82 | PDE2A (0.48) | MAPTTHRBHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL19492647 | 0.79 | KDM4C (0.36) | — | |
| SCHEMBL19492758 | 0.72 | MTNR1A (0.39) | MAPTHCRTR1HCRTR2KDM4EALDH1A1 | |
| SCHEMBL19492649 | 0.72 | PDE2A (0.36) | LMNA | |
| SCHEMBL31171097 | 0.71 | PDE2A (0.48) | ALDH1A1LMNACHRM4POLB | |
| SCHEMBL19492484 | 0.68 | THRB (0.39) | MAPTTHRBKDM4ELMNACSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442974-B1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| WO-2017178416-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |