Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19492761 | 0.85 | USP7 (0.39) | USP7PI4KBMAPTBRAFPOLB | |
| SCHEMBL19492624 | 0.77 | USP7 (0.33) | USP7BRAF | |
| SCHEMBL19463283 | 0.74 | MAPT (0.44) | MAPTPOLBTP53LMNA | |
| SCHEMBL19492643 | 0.72 | GRIN1 (0.33) | USP7 | |
| SCHEMBL28623625 | 0.71 | MAPT (0.34) | MAPTPOLBTP53LMNA | |
| SCHEMBL19493109 | 0.69 | GRIN1 (0.33) | — | |
| SCHEMBL19492659 | 0.68 | USP7 (0.39) | USP7BRAFTP53 | |
| SCHEMBL19492762 | 0.66 | DYRK3 (0.33) | USP7MAPT | |
| SCHEMBL19492751 | 0.63 | GABRG2 (0.31) | — | |
| SCHEMBL24455357 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442974-B1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| WO-2017178416-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |