Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19463283 | 0.89 | MAPT (0.44) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL28624802 | 0.87 | KMT2A (0.37) | MAPTMEN1KMT2AL3MBTL1KMO | |
| SCHEMBL28615710 | 0.84 | BRS3 (0.35) | MAPTDHODHMEN1KMT2AL3MBTL1 | |
| SCHEMBL20782378 | 0.81 | MAPT (0.44) | MAPTADORA1ALDH1A1POLBAKR1C3 | |
| SCHEMBL28619820 | 0.81 | MAPT (0.38) | MAPTDHODHADORA1ALDH1A1AKR1C3 | |
| SCHEMBL28618955 | 0.81 | AKR1C3 (0.37) | MAPTDHODHADORA1MEN1KMT2A | |
| SCHEMBL20768139 | 0.81 | KDM4E (0.39) | MAPTDHODHADORA1ALDH1A1AKR1C3 | |
| SCHEMBL19492764 | 0.71 | USP7 (0.33) | MAPTPOLBLMNATP53 | |
| SCHEMBL24455511 | 0.70 | MAPT (0.42) | MAPTDHODHMEN1KMT2AL3MBTL1 | |
| SCHEMBL22280894 | 0.70 | KDM4E (0.57) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |