Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768116 | 0.79 | PDE2A (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL19492644 | 0.71 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL20782378 | 0.63 | MAPT (0.44) | MAPTALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL15862655 | 0.63 | PDE2A (0.53) | POLBTGFBR1 | |
| SCHEMBL22280894 | 0.62 | KDM4E (0.57) | MAPTALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL19492615 | 0.62 | KDM4E (0.40) | MAPTALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL28981721 | 0.61 | POLB (0.40) | ALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL19463663 | 0.60 | KDM4E (0.50) | MAPTALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL29310630 | 0.60 | BTK (0.42) | TGFBR1 | |
| SCHEMBL20723160 | 0.59 | MAPT (0.48) | MAPTALDH1A1LMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442974-B1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| WO-2017178416-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |