Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19492615 | 0.89 | KDM4E (0.40) | ALDH1A1KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL19463663 | 0.83 | KDM4E (0.50) | ALDH1A1KDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL19492648 | 0.76 | LMNA (0.37) | TDP1SMN1; SMN2LMNAGAARAB9A | |
| SCHEMBL19492770 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KDM4ETDP1POLBCYP1A2 | |
| SCHEMBL20768126 | 0.72 | ALDH1A1 (0.35) | ALDH1A1KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL20768127 | 0.72 | PDE2A (0.55) | ALDH1A1POLBLMNAKMT2AMEN1 | |
| SCHEMBL19493110 | 0.71 | MAPT (0.40) | ALDH1A1KDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL19464016 | 0.70 | PPARA (0.37) | ALDH1A1KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL19464053 | 0.70 | KDM4E (0.43) | ALDH1A1KDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL19492870 | 0.69 | TDP1 (0.41) | ALDH1A1KDM4ETDP1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178416-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |