SCHEMBL19494774

SCHEMBL19494774

CC[N+](CC)=c1ccc2c(-c3ccccc3C(=O)O)c3ccc(O)cc3oc-2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 6/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ MEN1 O00255 5/20 0.48
▸ KMT2A Q03164 5/20 0.48
▸ POLB P06746 3/20 0.48
▸ ATM Q13315 2/20 0.48
▸ PLEC Q15149 1/20 0.48
▸ FTO Q9C0B1 2/20 0.47
▸ ALPL P05186 1/20 0.46
▸ ALPI P09923 1/20 0.46
▸ ALPG P10696 1/20 0.46
▸ BLM P54132 2/20 0.44
▸ PPARG P37231 1/20 0.44
▸ RXFP1 Q9HBX9 1/20 0.44
▸ NCOR2 Q9Y618 1/20 0.44
▸ DNASE1L3 Q13609 1/20 0.44
▸ PRMT1 Q99873 1/20 0.44
▸ FPR2 P25090 3/20 0.43
▸ HPGD P15428 3/20 0.43
▸ KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12763951 0.90 POLB (0.50) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL18637090 0.89 ABCB1 (0.56) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL17109310 0.89 ABCB1 (0.44) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL19494880 0.87 ABCB1 (0.45) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL16378797 0.86 FPR2 (0.44) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL19495008 0.86 ABCB1 (0.42) USP2L3MBTL1MEN1KMT2APOLB
SCHEMBL29593395 0.86 MEN1 (0.61) USP2MEN1KMT2APOLBFTO
SCHEMBL3903552 0.86 MEN1 (0.61) USP2MEN1KMT2APOLBFTO
SCHEMBL24818170 0.85 USP2 (0.42) USP2L3MBTL1MEN1KMT2APOLB
Hydrochloric Acid SCHEMBL18617 0.85 MEN1 (0.60) USP2MEN1KMT2APOLBFTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170342031-A1 QUENCHER WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2017-11-30 — — US disclosed
US-20170342031-A1 QUENCHER WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2017-11-30 — — US disclosed
EP-3235876-A1 QUENCHER Wako Pure Chemical Industries, Ltd. (JP) 2017-10-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170342031-A1 QUENCHER AHR, GFER, AKR1A1 USP2 3122/4885L3MBTL1 1158/4885MEN1 2721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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