Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19495358 | 0.90 | MEN1 (0.54) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12043094 | 0.85 | KDM4E (0.85) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14602136 | 0.78 | MEN1 (0.65) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2525573 | 0.77 | KDM4E (0.84) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14073362 | 0.75 | KDM4E (0.70) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12043096 | 0.75 | MEN1 (0.81) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12043100 | 0.74 | MEN1 (0.69) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14073364 | 0.72 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16940595 | 0.71 | KDM4E (0.74) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12043118 | 0.69 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937252-B1 | COMPOSITIONS FOR STIMULATING NEUROGENESIS AND INHIBITING NEURONAL DEGENERATION | NEURONASCENT INC (US) | 2017-10-25 | — | — | EP | disclosed |