SCHEMBL1949535

SCHEMBL1949535

CCC(C)C(=O)Nc1cc(NC(=O)C(C)CC)cc(NC(=O)C(C)CC)c1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.69
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA7 P43166 1/20 0.57
CA14 Q9ULX7 1/20 0.57
KMT2A Q03164 3/20 0.55
MEN1 O00255 1/20 0.55
HTT P42858 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
TSHR P16473 1/20 0.51
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 2/20 0.49
RAB9A P51151 1/20 0.49
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ADORA3 P0DMS8 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14341532 0.85 HSD17B10 (0.58) HSD17B10CA1CA2CA7CA14
SCHEMBL19752797 0.83 MEN1 (0.56) HSD17B10CA1CA2CA7CA14
SCHEMBL1947857 0.83 HSD17B10 (0.71) HSD17B10CA1CA2CA7CA14
SCHEMBL13989327 0.82 HSD17B10 (0.55) HSD17B10CA1CA2CA7CA14
SCHEMBL18456226 0.82 MME (0.63) HSD17B10CA1CA2CA7CA14
SCHEMBL4151615 0.82 MME (0.63) HSD17B10CA1CA2CA7CA14
SCHEMBL12205972 0.82 MME (0.63) HSD17B10CA1CA2CA7CA14
SCHEMBL1950228 0.81 HSD17B10 (0.49) HSD17B10CA1CA2CA7CA14
SCHEMBL12125174 0.80 CA1 (0.64) HSD17B10CA1CA2CA7CA14
SCHEMBL97700 0.80 CA1 (0.64) HSD17B10CA1CA2CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 US disclosed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP disclosed
US-8415416-B2 Electret materials BASF SE (DE) 2013-04-09 US disclosed
US-20130012091-A1 Electret Materials BASF SE (DE) 2013-01-10 US disclosed
EP-2510047-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2012-10-17 EP disclosed
US-20120184170-A1 Electret Materials CHIN HUI (US) 2012-07-19 US disclosed
US-20110230109-A1 Electret Materials CHIN HUI 2011-09-22 US disclosed
WO-2011071718-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2011-06-16 WO disclosed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 US disclosed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
WO-2010069854-A2 MODIFIED POLYOLEFIN WAXES BASF SE (DE) 2010-06-24 WO disclosed
US-20080249269-A1 Electret materials CIBA CORP. 2008-10-09 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP disclosed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO disclosed