SCHEMBL1949544

SCHEMBL1949544

CC(C)CC(=O)Nc1cc(NC(=O)CC(C)C)cc(C(=O)NC(C)(C)C)c1

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
LMNA P02545 4/20 0.49
MAPT P10636 1/20 0.49
PTPN1 P18031 1/20 0.49
ANO1 Q5XXA6 4/20 0.46
F2R P25116 2/20 0.46
GAA P10253 2/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HPGD P15428 1/20 0.44
KDM4E B2RXH2 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15180428 0.93 GAA (0.47) MEN1KMT2ALMNAMAPTPTPN1
SCHEMBL13178829 0.82 PTPN1 (0.68) MEN1KMT2ALMNAMAPTPTPN1
SCHEMBL27976288 0.78 ALDH1A1 (0.50) MEN1KMT2ALMNAMAPTANO1
SCHEMBL1946573 0.78 SMN1; SMN2 (0.48) LMNAPTPN1F2RGAARAB9A
SCHEMBL15119391 0.78 PTPN1 (0.54) MEN1KMT2ALMNAMAPTPTPN1
SCHEMBL5506280 0.77 LMNA (0.60) MEN1KMT2ALMNAMAPTANO1
SCHEMBL27976283 0.77 MEN1 (0.48) MEN1KMT2ALMNAMAPTANO1
SCHEMBL31477875 0.76 MEN1 (0.44) MEN1KMT2ALMNAMAPTANO1
SCHEMBL1948517 0.76 MEN1 (0.56) MEN1KMT2ALMNAMAPTANO1
SCHEMBL3078787 0.76 PTPN1 (0.56) MEN1KMT2ALMNAMAPTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP claimed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP claimed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 US claimed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US claimed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US claimed
JP-2006518402-A 2006-08-10 JP claimed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP claimed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO claimed
CN-115556446-A Decorative film and method for producing decorative molded body using same 日本聚丙烯株式会社 2023-01-03 CN disclosed
CN-115556441-A Decorative film and method for producing decorative molded body using same 日本聚丙烯株式会社 2023-01-03 CN disclosed
US-20200384678-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2020-12-10 US disclosed
EP-3715092-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME Japan Polypropylene Corporation (JP) 2020-09-30 EP disclosed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
WO-2007068766-A1 MONO- AND MULTI-LAYER BLOWN FILMS CIBA HOLDING INC. (CH) 2007-06-21 WO disclosed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP disclosed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO disclosed