Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 11/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 9/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 8/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720591 | 0.81 | MAPK9 (0.53) | MAPK9MAPK10MAPK8PPARGCCR2 | |
| SCHEMBL29456264 | 0.81 | MAPK9 (0.53) | MAPK9MAPK10MAPK8PPARGCCR2 | |
| SCHEMBL29456233 | 0.80 | KDM4E (0.48) | MAPK9MAPK10MAPK8PPARG | |
| SCHEMBL3780636 | 0.80 | KDM4E (0.48) | MAPK9MAPK10MAPK8PPARG | |
| SCHEMBL3782016 | 0.80 | MAPK9 (0.52) | MAPK9MAPK10MAPK8CCR2 | |
| SCHEMBL29456267 | 0.80 | MAPK9 (0.52) | MAPK9MAPK10MAPK8CCR2 | |
| SCHEMBL29456293 | 0.79 | MAPK9 (0.52) | MAPK9MAPK10MAPK8 | |
| SCHEMBL3783019 | 0.79 | MAPK9 (0.52) | MAPK9MAPK10MAPK8 | |
| Flucarbril SCHEMBL30086956 | 0.79 | BRPF1 (0.57) | — | |
| Flucarbril SCHEMBL2109672 | 0.79 | BRPF1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393806-B1 | INHIBITORS OF JUN N-TERMINAL KINASE | ELAN PHARM INC (US) | 2017-10-25 | — | — | EP | disclosed |