Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 6/20 | 0.60 |
| ▸ | RORC | P51449 | 6/20 | 0.53 |
| ▸ | GFER | P55789 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RORB | Q92753 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360994 | 0.87 | AOC3 (0.82) | AOC3 | |
| SCHEMBL19496954 | 0.82 | AOC3 (0.56) | AOC3GFERGAAMAPTSMN1; SMN2 | |
| SCHEMBL11358153 | 0.79 | AOC3 (0.58) | AOC3 | |
| SCHEMBL11364570 | 0.76 | AOC3 (0.79) | AOC3 | |
| SCHEMBL11359440 | 0.75 | AOC3 (1.00) | AOC3 | |
| SCHEMBL19496753 | 0.74 | AOC3 (0.79) | AOC3 | |
| SCHEMBL19496789 | 0.74 | AOC3 (0.76) | AOC3 | |
| SCHEMBL11364522 | 0.74 | AOC3 (0.84) | AOC3 | |
| SCHEMBL19496790 | 0.73 | AOC3 (0.62) | AOC3MAPT | |
| SCHEMBL19496723 | 0.72 | AOC3 (0.52) | AOC3MAPTSMN1; SMN2WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |