Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 9/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360494 | 0.83 | AOC3 (0.75) | AOC3 | |
| SCHEMBL19496721 | 0.78 | AOC3 (0.58) | AOC3 | |
| SCHEMBL19496954 | 0.76 | AOC3 (0.56) | AOC3TAAR1MAPTSMN1; SMN2 | |
| SCHEMBL11358644 | 0.76 | AOC3 (0.55) | AOC3 | |
| SCHEMBL19496853 | 0.72 | AOC3 (0.60) | AOC3MAPTSMN1; SMN2WNT3A | |
| SCHEMBL29864624 | 0.72 | TAAR1 (0.67) | AOC3TAAR1HTR7TSHRNMT1 | |
| SCHEMBL3464184 | 0.72 | TAAR1 (0.67) | AOC3TAAR1HTR7TSHRNMT1 | |
| SCHEMBL19496746 | 0.71 | AOC3 (0.59) | AOC3 | |
| SCHEMBL6132474 | 0.70 | MAPT (0.55) | MAPTTSHRSMN1; SMN2WNT3A | |
| SCHEMBL6132477 | 0.70 | MAPT (0.55) | MAPTTSHRSMN1; SMN2WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |