Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 7/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19496725 | 0.83 | GAA (0.54) | AOC3CHRNA7GAARAD52KDM4E | |
| SCHEMBL11364522 | 0.82 | AOC3 (0.84) | AOC3 | |
| SCHEMBL19496853 | 0.82 | AOC3 (0.60) | AOC3GAAMAPTGFERSMN1; SMN2 | |
| SCHEMBL12319455 | 0.79 | CHRNA7 (0.79) | CHRNA7GAARAD52KDM4EMAPT | |
| SCHEMBL10318103 | 0.79 | AOC3 (0.62) | AOC3MEN1KMT2A | |
| SCHEMBL19496722 | 0.77 | AOC3 (0.62) | AOC3 | |
| SCHEMBL19496723 | 0.76 | AOC3 (0.52) | AOC3MAPTSMN1; SMN2TAAR1 | |
| SCHEMBL19496553 | 0.75 | AOC3 (0.59) | AOC3 | |
| SCHEMBL19496700 | 0.74 | AOC3 (0.58) | AOC3 | |
| SCHEMBL3464184 | 0.74 | TAAR1 (0.67) | AOC3TAAR1CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |