Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367657 | 0.88 | AOC3 (0.70) | AOC3 | |
| SCHEMBL11360485 | 0.82 | AOC3 (0.52) | AOC3LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL11363728 | 0.80 | AOC3 (0.75) | AOC3 | |
| SCHEMBL2577808 | 0.79 | KMT2A (0.64) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL19496931 | 0.78 | AOC3 (0.56) | AOC3POLBLMNAMEN1KMT2A | |
| SCHEMBL23301380 | 0.78 | KMT2A (0.59) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL693919 | 0.76 | SMN1; SMN2 (0.51) | POLBLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL95957 | 0.76 | KMT2A (0.57) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL22290359 | 0.76 | MEN1 (0.56) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL23301111 | 0.75 | MGLL (0.56) | POLBLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |