Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363837 | 0.89 | AOC3 (0.74) | AOC3 | |
| SCHEMBL12814196 | 0.87 | AOC3 (0.60) | AOC3 | |
| SCHEMBL8157501 | 0.81 | SMN1; SMN2 (0.65) | HTR2BHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL11360718 | 0.81 | AOC3 (0.54) | AOC3HTR2BHTR1AHTR1BHTR2A | |
| SCHEMBL13952158 | 0.81 | HSD11B1 (0.54) | HTR2BSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL11363882 | 0.81 | AOC3 (0.71) | AOC3 | |
| SCHEMBL19496930 | 0.78 | AOC3 (0.52) | AOC3HRH3POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL11367453 | 0.78 | AOC3 (0.76) | AOC3 | |
| SCHEMBL11363836 | 0.77 | AOC3 (0.66) | AOC3 | |
| SCHEMBL11366262 | 0.77 | AOC3 (0.75) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |