Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 9/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19496728 | 0.86 | AOC3 (0.52) | AOC3AGXTHTR7SIGMAR1ADRA2A | |
| SCHEMBL11368318 | 0.85 | AOC3 (0.76) | AOC3 | |
| SCHEMBL11356512 | 0.78 | AOC3 (0.55) | AOC3 | |
| SCHEMBL19496908 | 0.73 | AOC3 (0.52) | AOC3PIK3CA | |
| SCHEMBL13940125 | 0.73 | MAPT (0.50) | AOC3 | |
| SCHEMBL11368336 | 0.72 | AOC3 (0.76) | AOC3 | |
| SCHEMBL19496954 | 0.70 | AOC3 (0.56) | AOC3 | |
| SCHEMBL30854973 | 0.70 | KDM4E (0.47) | AOC3DRD4 | |
| SCHEMBL30854969 | 0.70 | KDM4E (0.45) | AOC3AGXT | |
| SCHEMBL19496670 | 0.69 | AOC3 (0.61) | AOC3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |