Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 10/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | CALML3 | P27482 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19496971 | 0.86 | AOC3 (0.52) | AOC3AGXTHTR7PIK3CAMTOR | |
| SCHEMBL11368336 | 0.85 | AOC3 (0.76) | AOC3 | |
| SCHEMBL29789879 | 0.81 | WDR5 (0.56) | ADRA2AADRA2BADRA2CTMEM97SIGMAR1 | |
| SCHEMBL11356490 | 0.78 | AOC3 (0.55) | AOC3 | |
| SCHEMBL19496908 | 0.73 | AOC3 (0.52) | AOC3PIK3CA | |
| SCHEMBL13940125 | 0.73 | MAPT (0.50) | AOC3CYP1A2 | |
| SCHEMBL11368318 | 0.72 | AOC3 (0.76) | AOC3 | |
| SCHEMBL29789777 | 0.72 | WDR5 (0.54) | CALML3 | |
| SCHEMBL19496954 | 0.70 | AOC3 (0.56) | AOC3 | |
| SCHEMBL30854969 | 0.70 | KDM4E (0.45) | AOC3AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |