Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21559762 | 0.94 | POLB (0.35) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL15495194 | 0.90 | POLB (0.40) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL21663329 | 0.86 | POLB (0.37) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL19157295 | 0.86 | POLB (0.37) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL19497312 | 0.86 | BACE1 (0.45) | POLBAPEX1HTTTDP1FFAR1 | |
| SCHEMBL21693389 | 0.85 | POLB (0.40) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL19914777 | 0.85 | POLB (0.37) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL19624400 | 0.85 | ELANE (0.41) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL22537030 | 0.84 | HTT (0.38) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL19156792 | 0.84 | POLB (0.36) | ELANEPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170351130-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2017-12-07 | — | — | US | disclosed |