SCHEMBL19501005

SCHEMBL19501005

O=C(/C=C/c1ccccc1)Nc1cccc(NC(=O)Nc2ccccc2)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 12/20 0.78
MMP2 P08253 12/20 0.78
MMP9 P14780 12/20 0.78
EGFR P00533 8/20 0.78
MAOB P27338 5/20 0.78
MAOA P21397 4/20 0.78
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
HDAC3 O15379 1/20 0.66
HDAC4 P56524 1/20 0.66
HDAC1 Q13547 1/20 0.66
HDAC7 Q8WUI4 1/20 0.66
HDAC2 Q92769 1/20 0.66
HDAC8 Q9BY41 1/20 0.66
HDAC6 Q9UBN7 1/20 0.66
HDAC9 Q9UKV0 1/20 0.66
HDAC5 Q9UQL6 1/20 0.66
NPC1 O15118 1/20 0.66
MAPT P10636 1/20 0.66
ALPG P10696 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19501838 0.92 MMP1 (0.86) MMP1MMP2MMP9EGFRMAOB
N-Phenylcinnamamide SCHEMBL4205896 0.88 MMP1 (1.00) MMP1MMP2MMP9EGFRMAOB
N-Phenylcinnamamide SCHEMBL3667414 0.88 MMP1 (1.00) MMP1MMP2MMP9EGFRMAOB
N-Phenylcinnamamide SCHEMBL2682029 0.88 MMP1 (1.00) MMP1MMP2MMP9EGFRMAOB
SCHEMBL3590874 0.86 MMP1 (0.74) MMP1MMP2MMP9EGFRMAOB
SCHEMBL3590876 0.86 MMP1 (0.74) MMP1MMP2MMP9EGFRMAOB
SCHEMBL11590995 0.85 EGFR (0.92) MMP1MMP2MMP9EGFRMAOB
SCHEMBL9990629 0.84 MMP1 (1.00) MMP1MMP2MMP9EGFRMAOB
SCHEMBL6275812 0.84 MMP1 (1.00) MMP1MMP2MMP9EGFRMAOB
SCHEMBL6275814 0.84 MMP1 (1.00) MMP1MMP2MMP9EGFRMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10343438-B2 Heat-sensitive recording material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-07-09 US disclosed
US-20170297355-A1 Heat-Sensitive Recording Material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170297355-A1 Heat-Sensitive Recording Material SCN1A, SCN3A, KCNN3 MMP1 3235/4885MMP2 3203/4885MMP9 2397/4885
US-10343438-B2 Heat-sensitive recording material SCN1A, SCN3A, KCNN3 MMP1 3235/4885MMP2 3203/4885MMP9 2397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.