Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IAPP | P10997 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | PTEN | P60484 | 1/20 | 0.41 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768957 | 0.92 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL10750775 | 0.85 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL3242805 | 0.85 | KEAP1 (0.61) | ALDH1A1SLC6A3SMN1; SMN2PTPRBCDC25A | |
| SCHEMBL19501287 | 0.85 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL4234560 | 0.83 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL22047275 | 0.83 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL15504948 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP4F2CYP4A11TRPA1 | |
| SCHEMBL15504971 | 0.82 | SIRT2 (0.51) | ALDH1A1KDM4ELMNACYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL13736635 | 0.81 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL2027905 | 0.81 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170304255-A1 | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304255-A1 | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | PPARG, PPARD, PPARA | ALDH1A1 991/4885NPC1 795/4885RAB9A 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.