Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 9/20 | 0.65 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503299 | 0.93 | P2RY1 (0.69) | P2RY1P2RY2ADORA3HTR2CHTR2B | |
| SCHEMBL19503298 | 0.92 | P2RY1 (0.70) | P2RY1P2RY2ADORA3HTR2CHTR2B | |
| SCHEMBL21257364 | 0.88 | P2RY1 (0.66) | P2RY1 | |
| SCHEMBL16258261 | 0.87 | P2RY1 (0.66) | P2RY1P2RY2ADORA3 | |
| SCHEMBL21257376 | 0.86 | P2RY1 (0.64) | P2RY1P2RY2 | |
| SCHEMBL19503344 | 0.85 | ADORA3 (0.64) | P2RY1P2RY2ADORA3HTR2CHTR2B | |
| SCHEMBL21257367 | 0.81 | P2RY1 (0.70) | P2RY1P2RY2 | |
| SCHEMBL29318022 | 0.81 | P2RY1 (0.86) | P2RY1P2RY2ADORA3HTR2CHTR2B | |
| SCHEMBL19807533 | 0.81 | P2RY1 (0.58) | P2RY1P2RY2 | |
| SCHEMBL19503300 | 0.80 | P2RY1 (0.67) | P2RY1P2RY2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019157317-A1 | COMPOUNDS AND METHODS FOR TREATING ADDICTION AND RELATED DISORDERS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2019-08-15 | — | — | WO | disclosed |
| WO-2017185061-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-26 | — | — | WO | disclosed |