Oxirane

Oxirane

SCHEMBL1950487

C1CO1.NCCNCC1CO1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.38
CA6 P23280 3/20 0.38
CA7 P43166 3/20 0.38
CA9 Q16790 3/20 0.38
CA14 Q9ULX7 3/20 0.38
CA5B Q9Y2D0 3/20 0.38
MEN1 O00255 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CA2 P00918 2/20 0.36
CA3 P07451 2/20 0.36
CA4 P22748 2/20 0.36
CA5A P35218 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CA1 P00915 1/20 0.36
ALOX15 P16050 1/20 0.36
TP53 P04637 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxirane SCHEMBL11332029 0.96 CA12 (0.44) CA12CA6CA7CA9CA14
Oxirane SCHEMBL11312799 0.96 CA12 (0.44) CA12CA6CA7CA9CA14
SCHEMBL619340 0.93
SCHEMBL5935035 0.89 CA12 (0.50) CA12CA6CA7CA9CA14
SCHEMBL11309158 0.89 CA12 (0.50) CA12CA6CA7CA9CA14
SCHEMBL19530907 0.84
SCHEMBL10863469 0.83 CA12 (0.35) CA12CA6CA7CA9CA14
SCHEMBL28695414 0.81 CA12 (0.46) CA12CA6CA7CA9CA14
SCHEMBL11486967 0.79 ALDH1A1 (0.41) TDP1ALDH1A1TP53HTR1AADRA1D
SCHEMBL31573870 0.78 HTR1A (0.39) TDP1ALDH1A1TP53HTR1AADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10544323-B2 Dry colour systems and methods and easily dispersible formulations for use in such systems and methods DRIKOLOR INC (US) 2020-01-28 US disclosed
EP-3114173-A1 EASILY DISPERSIBLE FORMULATIONS OF PIGMENTS AND THEIR USE IN TINTING BASE MEDIA DRIKOLOR Inc (US) 2017-01-11 EP disclosed
US-20160369120-A1 DRY COLOUR SYSTEMS AND METHODS AND EASILY DISPERSIBLE FORMULATIONS FOR USE IN SUCH SYSTEMS AND METHODS D'ARCY POLYCHROME LIMITED (NZ) 2016-12-22 US disclosed
US-9441130-B2 Easily dispersible formulations of pigments and their use in tinting base media DRIKOLOR INC (US) 2016-09-13 US disclosed
US-9441137-B2 Easily dispersible formulations of pigments and their use in tinting base media DRIKOLOR INC (US) 2016-09-13 US disclosed
US-20160186007-A1 EASILY DISPERSIBLE FORMULATIONS OF PIGMENTS AND THEIR USE IN TINTING BASE MEDIA DRIKOLOR INC 2016-06-30 US disclosed
US-20150299492-A1 EASILY DISPERSIBLE FORMULATIONS OF PIGMENTS AND THEIR USE IN TINTING BASE MEDIA DRIKOLOR INC 2015-10-22 US disclosed
WO-2015133912-A1 EASILY DISPERSIBLE FORMULATIONS OF PIGMENTS AND THEIR USE IN TINTING BASE MEDIA D'ARCY POLYCHROME LIMITED (NZ) 2015-09-11 WO disclosed
US-20150252218-A1 Pigment formulations DRIKOLOR INC 2015-09-10 US disclosed
US-9120950-B1 Pigment formulations D'ARCY POLYCHROME LIMITED (NZ) 2015-09-01 US disclosed
EP-0557506-B1 PRINTING PLATE POLAROID CORP (US) 1998-11-04 EP disclosed
US-5296531-A Finishes for leather BASF AKTIENGESELLSCHAFT (DE) 1994-03-22 US disclosed
EP-0557506-A1 PRINTING PLATE POLAROID CORPORATION (US) 1993-09-01 EP disclosed
WO-1993005446-A1 PRINTING PLATE POLAROID CORPORATION (US) 1993-03-18 WO disclosed
EP-0138748-B1 FLUOROALIPHATIC -THIO, -SULFINYL OR -SULFONYL SUBSTITUTED BICYCLOALIPHATIC AMIC ACID AMINE SALTS AND COMPOSITIONS AND USE THEREOF CIBA-GEIGY AG (CH) 1987-01-21 EP disclosed
US-4590129-A OIL AND WATER REPELLENT FOR CELLULOSE AND POLYAMIDES CIBA-GEIGY CORPORATION (US) 1986-05-20 US disclosed
US-4536254-A OIL AND WATER REPELLENTS CIBA-GEIGY CORPORATION (US) 1985-08-20 US disclosed
US-4515640-A RENDERING CELLULOSE AND POLYAMIDES OIL AND WATER REPELLENT CIBA GEIGY CORPORATION (US) 1985-05-07 US disclosed
EP-0138748-A1 Fluoroaliphatic -thio, -sulfinyl or -sulfonyl substituted bicycloaliphatic amic acid amine salts and compositions and use thereof CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed
US-4419298-A OIL AND WATER REPELLENTS CIBA-GEIGY CORPORATION (US) 1983-12-06 US disclosed