Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20877367 | 0.73 | NOS1 (0.36) | SMN1; SMN2 | |
| SCHEMBL3200515 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2 | |
| SCHEMBL2979310 | 0.70 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL22705132 | 0.69 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL19475427 | 0.68 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL19505689 | 0.67 | SMN1; SMN2 (0.35) | SMN1; SMN2 | |
| SCHEMBL24784411 | 0.62 | HCAR2 (0.39) | SMN1; SMN2 | |
| SCHEMBL20692397 | 0.61 | PSEN1 (0.30) | — | |
| SCHEMBL20698940 | 0.61 | PSEN1 (0.30) | — | |
| SCHEMBL3385702 | 0.60 | GAA (0.40) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445757-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RES INC (US) | 2020-11-25 | — | — | EP | disclosed |
| WO-2017184624-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | IFM THERAPEUTICS, INC (US) | 2017-10-26 | — | — | WO | disclosed |