⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20191707 | 1.00 | — | — | |
| SCHEMBL16155262 | 0.80 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL20191620 | 0.80 | CA2 (0.32) | — | |
| SCHEMBL19506798 | 0.80 | CA2 (0.32) | — | |
| SCHEMBL13709416 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL13707292 | 0.75 | CA2 (0.30) | — | |
| SCHEMBL2914959 | 0.74 | MEN1 (0.41) | — | |
| SCHEMBL20191623 | 0.73 | — | — | |
| SCHEMBL16149640 | 0.72 | SMYD2 (0.39) | — | |
| SCHEMBL5349777 | 0.72 | CA2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242565-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | ZIKANI THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-06-13 | — | — | US | disclosed |
| US-9982005-B2 | Macrolides and methods of their preparation and use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-05-29 | — | — | US | disclosed |
| US-20170305953-A1 | 14-MEMBERED KETOLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-10-26 | — | — | US | disclosed |