SCHEMBL19507465

SCHEMBL19507465

c1ccc(-c2nc3ccccc3nc2-c2ccc(-n3c4ccccc4c4cc5ccccc5cc43)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.45
KDM4E B2RXH2 4/20 0.45
ATM Q13315 2/20 0.45
ALDH1A1 P00352 4/20 0.43
LMNA P02545 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
GAA P10253 1/20 0.43
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
THRB P10828 1/20 0.40
NPY5R Q15761 1/20 0.39
AKT1 P31749 1/20 0.38
AKT2 P31751 1/20 0.38
POLB P06746 1/20 0.38
HSD17B10 Q99714 1/20 0.38
DHODH Q02127 1/20 0.38
PDE10A Q9Y233 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21168852 0.96 L3MBTL1 (0.45) L3MBTL1KDM4EATMALDH1A1LMNA
SCHEMBL21716216 0.96 L3MBTL1 (0.41) L3MBTL1KDM4EATMALDH1A1LMNA
SCHEMBL21168917 0.96 L3MBTL1 (0.45) L3MBTL1KDM4EATMALDH1A1LMNA
SCHEMBL21716715 0.96 L3MBTL1 (0.41) L3MBTL1KDM4EATMALDH1A1LMNA
SCHEMBL21716946 0.95 L3MBTL1 (0.41) L3MBTL1KDM4EATMALDH1A1LMNA
SCHEMBL21717504 0.95 L3MBTL1 (0.41) L3MBTL1KDM4EATMALDH1A1LMNA
SCHEMBL21168854 0.93 L3MBTL1 (0.39) L3MBTL1KDM4EATMALDH1A1LMNA
SCHEMBL24474738 0.92 PIK3R1 (0.41) L3MBTL1KDM4EATMALDH1A1LMNA
SCHEMBL21213301 0.92 L3MBTL1 (0.39) L3MBTL1KDM4EATMALDH1A1LMNA
SCHEMBL20886601 0.92 L3MBTL1 (0.51) L3MBTL1KDM4EATMALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11581496-B2 Benzocarbazole-based compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-02-14 US disclosed
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-06-02 US disclosed
US-20190237680-A1 BENZOCARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2019-08-01 US disclosed
US-20190131542-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2019-05-02 US disclosed
WO-2017183859-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190237680-A1 BENZOCARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CYP1B1, CYP2C9, CYP3A4 L3MBTL1 898/4885KDM4E 879/4885ATM 4058/4885
US-11581496-B2 Benzocarbazole-based compound and organic light-emitting device comprising same CYP1B1, CYP2C9, CYP3A4 L3MBTL1 898/4885KDM4E 879/4885ATM 4058/4885
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LEF1, ODC1, OR10J3 L3MBTL1 772/4885KDM4E 1293/4885ATM 2614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.