Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB4 | Q15303 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 8/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18633117 | 0.70 | ERBB4 (0.51) | ERBB4EGFR | |
| SCHEMBL15106807 | 0.69 | EGFR (0.62) | EGFR | |
| SCHEMBL24413789 | 0.66 | CSF1R (0.46) | ERBB4EGFRRAB9A | |
| SCHEMBL15090494 | 0.66 | EGFR (0.81) | ERBB4EGFR | |
| SCHEMBL20415682 | 0.65 | LMNA (0.42) | EGFRRAB9A | |
| SCHEMBL21761329 | 0.65 | EGFR (0.47) | ERBB4EGFR | |
| SCHEMBL18633116 | 0.65 | ERBB4 (0.57) | ERBB4EGFR | |
| SCHEMBL18873071 | 0.65 | EGFR (0.48) | ERBB4EGFR | |
| SCHEMBL24535646 | 0.65 | EGFR (0.41) | EGFR | |
| SCHEMBL18595973 | 0.65 | EGFR (0.50) | ERBB4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170304305-A1 | QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF | XUANZHU PHARMA CO LTD (CN) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304305-A1 | QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF | NQO2, CHRM1, CHRM2 | ERBB4 1431/4885EGFR 983/4885MCHR1 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.