SCHEMBL1950779

SCHEMBL1950779

Nc1cnc2ccccc2c1NCCOCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.39
HPGD P15428 3/20 0.38
HRH3 Q9Y5N1 1/20 0.38
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38
RAB9A P51151 6/20 0.38
NPC1 O15118 3/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15722137 0.86 MEN1 (0.46) NPSR1HPGDHRH3RAB9AMEN1
Hydrochloric Acid SCHEMBL8132994 0.84 MEN1 (0.46) NPSR1HPGDHRH3ACHEMEN1
SCHEMBL1949284 0.83 ALDH1A1 (0.44) NPSR1HPGDHRH3RAB9ANPC1
SCHEMBL3170264 0.79 KMT2A (0.46) HPGDHRH3BCHEACHERAB9A
SCHEMBL10123175 0.75 KMT2A (0.41) HRH3BCHEACHERAB9ANPC1
SCHEMBL6800384 0.74 GBA1 (0.46) NPSR1BCHEACHERAB9ANPC1
SCHEMBL1039304 0.72 MEN1 (0.44) BCHERAB9ANPC1MEN1KMT2A
SCHEMBL6096807 0.71 HTR1A (0.51) HRH3BCHEACHE
SCHEMBL3485508 0.71 HPGD (0.51) NPSR1HPGDACHERAB9ANPC1
SCHEMBL7171113 0.71 KMT2A (0.40) NPSR1BCHEACHERAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2507237-A1 IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) Dainippon Sumitomo Pharma Co., Ltd. (JP) 2012-10-10 EP disclosed
WO-2011068233-A1 IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2011-06-09 WO disclosed
US-20110136801-A1 Novel Compounds DAINIPPON SUMITOMO PHARMA CO. LTD. (JP) 2011-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136801-A1 Novel Compounds C1R, RB1, CNKSR1 NPSR1 201/4885HPGD 4048/4885HRH3 495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.