Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.40 |
| ▸ | SRC | P12931 | 7/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | BRD1 | O95696 | 5/20 | 0.36 |
| ▸ | BRPF3 | Q9ULD4 | 4/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.33 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480859 | 0.80 | BRPF1 (0.43) | BRPF1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL502548 | 0.76 | SRC (0.47) | BRPF1ALDH1A1FGFR1SRC | |
| SCHEMBL30754455 | 0.75 | BRPF1 (0.47) | BRPF1KDM4EFGFR1SRCCYP1A2 | |
| SCHEMBL27383191 | 0.75 | AHR (0.35) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL27383051 | 0.75 | RIPK2 (0.45) | FGFR1SRC | |
| SCHEMBL14145303 | 0.74 | SRC (0.40) | KDM4EFGFR1SRCCYP2A6 | |
| SCHEMBL10813893 | 0.74 | BRPF1 (0.54) | BRPF1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL19508038 | 0.74 | ALDH1A1 (0.62) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL24665079 | 0.74 | FGFR1 (0.45) | FGFR1SRCBRD4 | |
| SCHEMBL502525 | 0.73 | MAPK14 (0.53) | KDM4EALDH1A1HPGDFGFR1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305918-A1 | DUAL-WARHEAD COVALENT INHIBITORS OF FGFR-4 | NEWAVE PHARMACEUTICAL INC. | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305918-A1 | DUAL-WARHEAD COVALENT INHIBITORS OF FGFR-4 | FGFR4, FGFR2, FGFR3 | BRPF1 839/4885KDM4E 214/4885ALDH1A1 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.