SCHEMBL19508516

SCHEMBL19508516

CCCCC1C(=O)NC(=O)C1I

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
ELANE P08246 1/20 0.35
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
PRKCA P17252 1/20 0.32
DAGLA Q9Y4D2 1/20 0.31
CYP19A1 P11511 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
HLCS P50747 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15820503 0.85 ALDH1A1 (0.52) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL15821046 0.79 ALDH1A1 (0.45) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL8586448 0.78 ALDH1A1 (0.46) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL9408903 0.77 ALDH1A1 (0.44) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL6598025 0.76 ALDH1A1 (0.44) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL10649691 0.72 DAGLA (0.41) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL9063018 0.72 ALDH1A1 (0.76) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL5617173 0.71 DAGLA (0.43) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL23048857 0.70 MEN1 (0.36) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL14571743 0.70 ALDH1A1 (0.41) ALDH1A1KDM4EMEN1MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9909066-B2 Alignment layer composition, liquid crystal display including the alignment layer composition, and manufacturing method of the liquid crystal display SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-06 US disclosed
US-20170306236-A1 ALIGNMENT LAYER COMPOSITION, LIQUID CRYSTAL DISPLAY INCLUDING THE ALIGNMENT LAYER COMPOSITION, AND MANUFACTURING METHOD OF THE LIQUID CRYSTAL DISPLAY SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-26 US disclosed