Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HLCS | P50747 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15820503 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL15821046 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL8586448 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL9408903 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL19508516 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL10649691 | 0.72 | DAGLA (0.41) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL9063018 | 0.72 | ALDH1A1 (0.76) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL5617173 | 0.71 | DAGLA (0.43) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL8469066 | 0.67 | EPHX2 (0.40) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL2580220 | 0.66 | ALDH1A1 (0.67) | ALDH1A1KDM4EMEN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201664-B1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2004-09-08 | — | — | EP | disclosed |
| US-6593323-B1 | Benzimidazole compound inhibitory action of forming of macrophages and is useful as an active ingredient of a medicament for preventive and/or therapeutic treatment of arteriosclerosis, which is represented by the formula (I): | FUJI PHOTO FILM CO., LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1201664-A1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 2002-05-02 | — | — | EP | disclosed |