⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181552 | 1.00 | — | — | |
| SCHEMBL27645368 | 0.97 | PNMT (0.60) | — | |
| SCHEMBL5343562 | 0.97 | PNMT (0.60) | — | |
| SCHEMBL11633566 | 0.87 | PNMT (0.50) | — | |
| SCHEMBL8993096 | 0.84 | PNMT (0.52) | — | |
| SCHEMBL225197 | 0.83 | TSHR (0.54) | — | |
| SCHEMBL3300276 | 0.81 | PNMT (0.65) | — | |
| SCHEMBL12050856 | 0.81 | TAAR1 (0.74) | — | |
| SCHEMBL10879878 | 0.81 | FADS1 (0.46) | — | |
| SCHEMBL11315543 | 0.81 | CYP3A4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2156 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120071332-A | Tomato maturity detection method based on edge space feature fusion and feature focusing | 淮阴工学院 | 2025-05-30 | — | — | CN | claimed |
| CN-115959962-B | Visible light-promoted halogenated alkane hydrodehalogenation method | 中国科学院兰州化学物理研究所 | 2025-05-23 | — | — | CN | claimed |
| CN-115850002-B | Method for hydrodehalogenating halogenated alkane | 中国科学院兰州化学物理研究所 | 2025-05-23 | — | — | CN | claimed |
| CN-119708044-A | Andrographolide derivative containing thiazolidine ketone heterocycle, preparation method and application thereof | 西北农林科技大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119504343-A | Meta-methyl chlorobenzyl production process and production system thereof | 安徽苏乐医药材料有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119444690-A | Breast cancer tissue image classifying method based on multiscale characteristic fusion and attention mechanism | 长春大学 | 2025-02-14 | — | — | CN | claimed |
| CN-119060019-A | Quinazolines heterocyclic compound for ship antifouling and preparation method thereof | 净峰科技(舟山)有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-118812350-A | Method for synthesizing m-chlorobenzoyl chloride from m-chlorotoluene | 江苏聚由新材料科技有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-118666932-A | Cholesterol oxime ester/oxime ether derivative, preparation method and application | 西北农林科技大学 | 2024-09-20 | — | — | CN | claimed |
| CN-118146068-A | Method for preparing (substituted) benzyl alcohol/aldehyde by rapid phase transfer hydrolysis of benzyl chloride | 南京工业大学 | 2024-06-07 | — | — | CN | claimed |
| EP-1442035-B1 | PROCESS FOR THE PREPARATION OF 4- (8-CHLORO-5, 6-DIHYDRO-11H-BENZO-[5,6]-CYCLOHEPTA-[1,2-B]-PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER (LORATADINE) | ZAMBON SPA (IT) | 2006-01-11 | — | — | EP | claimed |
| US-20050202316-A1 | positive electrode comprising a combination of positive active materials, a lithium oxides of nickel, manganese, cobalt and one other metal; improve cycle life at room temperature and high temperatures, and enhanced safety with increased capacity | SAMSUNG SDI CO., LTD. (KR) | 2005-09-15 | — | — | US | claimed |
| US-20050171352-A1 | Process for the preparation of 4-(8-chloro-5 6-dihydro-11h-benzo-(5 6)-cyclohepta-(1 2b)-pyridin-11-ylidene-1-piperidiniecarboxylic acid ethyl ester (loratadine) | ZAMBON GROUP S.P.A (IT) | 2005-08-04 | — | — | US | claimed |
| US-20050089759-A1 | Rechargeable lithium polymer battery | SAMSUNG SDI CO., LTD. (KR) | 2005-04-28 | — | — | US | claimed |
| US-20050084760-A1 | Rechargeable lithium ion battery | SAMSUNG SDI CO., LTD. (KR) | 2005-04-21 | — | — | US | claimed |
| CN-1599736-A | Process for the preparation of 4-(8-chloro-5,6-dihydro-11h-benzo(5,6)-cyclohepta-(1,2b)-pyridin-11-ylidene)-1-piperidinecarboxyli c acid ethyl ester (loratadine) | ZAMBON SPA (IT) | 2005-03-23 | — | — | CN | claimed |
| EP-1442035-A1 | PROCESS FOR THE PREPARATION OF 4- (8-CHLORO-5, 6-DIHYDRO-11H-BENZO-[5,6]-CYCLOHEPTA-[1,2-B]-PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER (LORATADINE) | ZAMBON GROUP S.p.A. (IT) | 2004-08-04 | — | — | EP | claimed |
| WO-2003040140-A1 | PROCESS FOR THE PREPARATION OF 4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO(5,6)-CYCLOHEPTA-(1,2B)-PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLI C ACID ETHYL ESTER (LORATADINE) | ZAMBON GROUP S.P.A. (IT) | 2003-05-15 | — | — | WO | claimed |
| US-20010039349-A1 | Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds | SHELL OIL COMPANY | 2001-11-08 | — | — | US | claimed |
| US-6201161-B1 | Method of reducing benzaldehyde or benzotrihalide content in a mixture | OCCIDENTAL CHEMICAL CORPORATION | 2001-03-13 | — | — | US | claimed |