Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 6/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007523 | 0.79 | KDM4E (0.32) | BRD4 | |
| SCHEMBL16244550 | 0.73 | GAA (0.46) | BRD4BRD2 | |
| SCHEMBL16244552 | 0.73 | GAA (0.46) | BRD4BRD2 | |
| SCHEMBL24370012 | 0.73 | BRD4 (0.35) | BRD4 | |
| SCHEMBL12659550 | 0.73 | BRD4 (0.53) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL13604348 | 0.72 | MAPT (0.44) | — | |
| SCHEMBL22600101 | 0.71 | BRD4 (0.47) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL16060757 | 0.70 | BRD4 (0.50) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL22516630 | 0.70 | BRD4 (0.50) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL15148291 | 0.70 | BRD4 (0.50) | BRD4BRD9BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855483-B1 | PYRROLOPYRROLIDINONE COMPOUNDS | NOVARTIS AG (CH) | 2017-10-25 | — | — | EP | disclosed |