Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 9/20 | 0.45 |
| ▸ | BRD2 | P25440 | 3/20 | 0.45 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155870 | 0.78 | BRD4 (0.41) | BRD4BRD9CREBBPALDH1A1 | |
| SCHEMBL10312581 | 0.75 | CRHR1 (0.39) | BRD4CYP19A1NQO2THRB | |
| SCHEMBL12659550 | 0.73 | BRD4 (0.53) | BRD4BRD9BRD2BRD7BRD3 | |
| SCHEMBL19513633 | 0.71 | BRD4 (0.47) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL23134699 | 0.71 | BRD4 (0.68) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL19513637 | 0.71 | BRD4 (0.43) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL31180701 | 0.70 | MAOB (0.49) | BRD4BRD9BRD2BRD3CREBBP | |
| SCHEMBL28506607 | 0.70 | BRD4 (0.58) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL2118787 | 0.70 | BRD4 (0.50) | BRD4BRD9BRD2BRD7CREBBP | |
| SCHEMBL22516630 | 0.70 | BRD4 (0.50) | BRD4BRD9BRD2BRD7BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020219168-A1 | SMALL MOLECULE BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE, LLC (US) | 2020-10-29 | — | — | WO | disclosed |