SCHEMBL195182

SCHEMBL195182

C=C(C)C(=O)OCCCCOC(=O)/C=C\C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 9/20 0.64
TSHR P16473 5/20 0.56
ATM Q13315 1/20 0.48
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
THRB P10828 1/20 0.44
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9514358 0.97 HCAR2 (0.61) HCAR2TSHRATMPOLBAPEX1
SCHEMBL195022 0.97 HCAR2 (0.61) HCAR2TSHRATMPOLBAPEX1
SCHEMBL1886812 0.93 HCAR2 (0.58) HCAR2TSHRATMPOLBAPEX1
SCHEMBL194313 0.93 HCAR2 (0.58) HCAR2TSHRATMPOLBAPEX1
SCHEMBL698817 0.93 HCAR2 (0.58) HCAR2TSHRATMPOLBAPEX1
SCHEMBL5082364 0.93 HCAR2 (0.58) HCAR2TSHRATMPOLBAPEX1
SCHEMBL2530701 0.93 TSHR (0.63) HCAR2TSHRATMPOLBAPEX1
SCHEMBL29132466 0.92 HCAR2 (0.56) HCAR2TSHRATMPOLBAPEX1
SCHEMBL28190015 0.91 HCAR2 (0.56) HCAR2TSHRATMPOLBAPEX1
SCHEMBL14007296 0.89 HCAR2 (0.53) HCAR2TSHRATMPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10004673-B1 Hair treatment composition comprising Michael addition product and methods for treating hair L'OREAL (FR) 2018-06-26 US claimed
EP-0325038-B1 Surface priming composition for proteinaceous substrates, method of making and using same OPI PROD INC (US) 1993-11-03 EP claimed
US-4913939-A Reaction product of cyclic anhydride and hydroxy compound; adhesion of adhesives REM SYSTEMS, INC. (US) 1990-04-03 US claimed
US-4863993-A Surface priming composition for proteinaceous substrates; method of making and using same OPI PRODUCTS, INC. (US) 1989-09-05 US claimed
EP-0325038-A2 Surface priming composition for proteinaceous substrates, method of making and using same OPI PRODUCTS, INC. (US) 1989-07-26 EP claimed
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
EP-4114825-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-01-11 EP disclosed
US-20220121113-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2022-04-21 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
EP-3044208-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-12-22 EP disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
WO-2006024617-A1 COMPOSITIONS CONTAINING ANTHRAQUINONE DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 WO disclosed
WO-2006018405-A1 OXIME ESTER PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-02-23 WO disclosed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 EP disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed
EP-0325038-B1 Surface priming composition for proteinaceous substrates, method of making and using same OPI PROD INC (US) 1993-11-03 EP disclosed
US-4913939-A Reaction product of cyclic anhydride and hydroxy compound; adhesion of adhesives REM SYSTEMS, INC. (US) 1990-04-03 US disclosed
US-4863993-A Surface priming composition for proteinaceous substrates; method of making and using same OPI PRODUCTS, INC. (US) 1989-09-05 US disclosed
EP-0325038-A2 Surface priming composition for proteinaceous substrates, method of making and using same OPI PRODUCTS, INC. (US) 1989-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HCAR2 1784/4885TSHR 528/4885ATM 3078/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HCAR2 1610/4885TSHR 519/4885ATM 3037/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HCAR2 1784/4885TSHR 528/4885ATM 3078/4885
US-10004673-B1 Hair treatment composition comprising Michael addition product and methods for treating hair SRM, CRAT, C9 HCAR2 1735/4885TSHR 1844/4885ATM 1093/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 HCAR2 1233/4885TSHR 2202/4885ATM 1370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.