Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.59 |
| ▸ | SELL | P14151 | 2/20 | 0.58 |
| ▸ | SELP | P16109 | 2/20 | 0.58 |
| ▸ | SELE | P16581 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434850 | 0.86 | MEN1 (0.83) | KMT2AMEN1TPSAB1CYP3A4GAA | |
| SCHEMBL14623873 | 0.86 | MEN1 (0.83) | KMT2AMEN1TPSAB1CYP3A4GAA | |
| SCHEMBL9787431 | 0.85 | EPHX2 (0.75) | KMT2AMEN1EPHX2HDAC3HDAC4 | |
| SCHEMBL21998923 | 0.85 | EPHX2 (0.75) | KMT2AMEN1EPHX2HDAC3HDAC4 | |
| SCHEMBL9787405 | 0.85 | EPHX2 (0.75) | KMT2AMEN1EPHX2HDAC3HDAC4 | |
| SCHEMBL9787358 | 0.85 | EPHX2 (0.75) | KMT2AMEN1EPHX2HDAC3HDAC4 | |
| SCHEMBL9787410 | 0.85 | EPHX2 (0.75) | KMT2AMEN1EPHX2HDAC3HDAC4 | |
| SCHEMBL10741431 | 0.85 | EPHX2 (0.75) | KMT2AMEN1EPHX2HDAC3HDAC4 | |
| SCHEMBL19865073 | 0.84 | TPSAB1 (0.63) | KMT2AMEN1TPSAB1CYP3A4CA1 | |
| SCHEMBL8499126 | 0.84 | MEN1 (0.80) | KMT2AMEN1TPSAB1CYP3A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067670-A1 | IRINOTECAN IMMUNOASSAY | SALADAX BIOMEDICAL INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| US-20110165699-A1 | IRINOTECAN IMMUNOASSAY | SHANGHAI FOSUN PHARMACEUTICAL (GROUP) CO., LTD. (CN) | 2011-07-07 | — | — | US | disclosed |
| WO-2011071672-A1 | IRINOTECAN IMMUNOASSAY | SALADAX BIOMEDICAL INC. (US) | 2011-06-16 | — | — | WO | disclosed |
| US-20110136253-A1 | Irinotecan Immunoassay | SHANGHAI FOSUN PHARMACEUTICAL (GROUP) CO., LTD. (CN) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165699-A1 | IRINOTECAN IMMUNOASSAY | SI, TOP2A, TYMP | KMT2A 3709/4885MEN1 3394/4885TPSAB1 531/4885 |
| US-20110136253-A1 | Irinotecan Immunoassay | SI, TOP2A, TYMP | KMT2A 3709/4885MEN1 3394/4885TPSAB1 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.