⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxypurinol SCHEMBL2077651 | 0.83 | — | — | |
| SCHEMBL15397499 | 0.72 | MAPK1 (0.32) | — | |
| SCHEMBL95393 | 0.68 | — | — | |
| Allopurinol SCHEMBL167561 | 0.67 | CCNE2 (0.31) | — | |
| SCHEMBL1952036 | 0.64 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL162535 | 0.62 | ADORA3 (0.36) | — | |
| SCHEMBL5880789 | 0.60 | DYRK1A (0.38) | — | |
| SCHEMBL1724116 | 0.60 | GDA (0.41) | — | |
| Tisopurine SCHEMBL7160585 | 0.58 | — | — | |
| SCHEMBL11326338 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851435-B2 | PTGR2 inhibitors and their use | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2023-12-26 | — | — | US | disclosed |
| US-20230279008-A1 | PTGR2 INHIBITORS AND THEIR USE | NATIONAL TAIWAN UNIVERSITY (TW) | 2023-09-07 | — | — | US | disclosed |
| EP-2271630-B1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2016-03-23 | — | — | EP | disclosed |
| US-8592432-B2 | Compounds and compositions as protein kinase inhibitors | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2013-11-26 | — | — | US | disclosed |
| US-20110135668-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2011-06-09 | — | — | US | disclosed |
| WO-2009126515-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-10-15 | — | — | WO | disclosed |
| US-RE38416-E1 | NUCLEOTIDE BASES COMPRISING PYRAZOLO(3,4-D)PYRIMIDINES USED FOR MEDICAL DIAGNOSIS, THERAPY, HYBRIDIZATION, ANTISENSE AGENTS OR REPORTER MOLECULES | EPOCH BIOSCIENCES, INC. | 2004-02-03 | — | — | US | disclosed |
| EP-0881875-A4 | COMPOSITIONS AND METHODS FOR CONTROLLING PEST INSECTS | VIRGINIA TECH INTELL PROP (US) | 2002-03-06 | — | — | EP | disclosed |
| US-6037344-A | COMPRISING A PURINE SELECTED FROM THE GROUP CONSISTING OF XANTHINE, HYPOXANTHINE, GUANINE AND MIXTURES THEREOF, AND A XANTHINE OXIDASE INHIBITOR SELECTED FROM THE GROUP CONSISTING OF ALLOPURINOL, OXYPURINOL, MERCAPTO-ALLOPURINOL, | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2000-03-14 | — | — | US | disclosed |
| US-5990115-A | Compositions and methods for controlling pest insects | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0881875-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PEST INSECTS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0842186-A1 | CROSS-LINKING OLIGONUCLEOTIDES | MICROPROBE CORPORATION (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997028686-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PEST INSECTS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1997-08-14 | — | — | WO | disclosed |
| WO-1997012896-A1 | SELECTIVE BINDING COMPLEMENTARY OLIGONUCLEOTIDES | EPOCH PHARMACEUTICALS, INC. (US) | 1997-04-10 | — | — | WO | disclosed |
| WO-1996040711-A1 | CROSS-LINKING OLIGONUCLEOTIDES | MICROPROBE CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0661979-A4 | CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION. | MICROPROBE CORP (US) | 1995-09-13 | — | — | EP | disclosed |
| EP-0661979-A1 | CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION | MICROPROBE CORPORATION (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1993003736-A1 | CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION | MICROPROBE CORPORATION (US) | 1993-03-04 | — | — | WO | disclosed |
| WO-1990003370-A1 | DERIVATIVES OF PYRAZOLO[3,4-d]PYRIMIDINE | MICROPROBE CORPORATION (US) | 1990-04-05 | — | — | WO | disclosed |