⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014919 | 0.79 | PDPK1 (0.39) | — | |
| Oxypurinol SCHEMBL2077651 | 0.79 | — | — | |
| SCHEMBL7635291 | 0.76 | — | — | |
| SCHEMBL1952035 | 0.68 | — | — | |
| SCHEMBL839587 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL1741651 | 0.65 | PI4KA (0.44) | — | |
| Hydrochloric Acid SCHEMBL14742344 | 0.65 | PI4KA (0.44) | — | |
| SCHEMBL95394 | 0.64 | XDH (0.52) | — | |
| SCHEMBL5144478 | 0.64 | ADORA2A (0.44) | — | |
| SCHEMBL19236510 | 0.63 | CYP1A2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980554-B1 | HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES | HOFFMANN LA ROCHE (CH) | 2025-03-26 | — | — | EP | claimed |
| US-20220195497-A1 | HYBRIDIZING all-LNA OLIGONUCLEOTIDES | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2022-06-23 | — | — | US | claimed |
| EP-3980554-A1 | HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES | F. Hoffmann-La Roche AG (CH) | 2022-04-13 | — | — | EP | claimed |
| CN-113939599-A | Hybrid all-LNA oligonucleotides | 豪夫迈·罗氏有限公司 | 2022-01-14 | — | — | CN | claimed |
| WO-2020245377-A1 | HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-12-10 | — | — | WO | claimed |
| US-7829596-B2 | Methods of treatment | IMPERIAL INNOVATIONS LIMITED (GB) | 2010-11-09 | — | — | US | claimed |
| US-20090023639-A1 | Methods of Treatment | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-01-22 | — | — | US | claimed |
| EP-0759298-B1 | Use of 4-amino-6-hydroxypyrazolo[3,4-d]pyrimidine for the manufacture of an antihypertensive agent | MAEDA HIROSHI DR (JP) | 2003-11-05 | — | — | EP | claimed |
| EP-0881875-A4 | COMPOSITIONS AND METHODS FOR CONTROLLING PEST INSECTS | VIRGINIA TECH INTELL PROP (US) | 2002-03-06 | — | — | EP | claimed |
| US-6281222-B1 | Compositions and method for treatment of acetaminophen intoxication | INOTEK CORPORATION | 2001-08-28 | — | — | US | claimed |
| WO-2000021509-A2 | METHODS OF TREATMENT | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2000-04-20 | — | — | WO | claimed |
| US-6037344-A | COMPRISING A PURINE SELECTED FROM THE GROUP CONSISTING OF XANTHINE, HYPOXANTHINE, GUANINE AND MIXTURES THEREOF, AND A XANTHINE OXIDASE INHIBITOR SELECTED FROM THE GROUP CONSISTING OF ALLOPURINOL, OXYPURINOL, MERCAPTO-ALLOPURINOL, | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2000-03-14 | — | — | US | claimed |
| EP-0881875-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PEST INSECTS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1998-12-09 | — | — | EP | claimed |
| WO-1997028686-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PEST INSECTS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1997-08-14 | — | — | WO | claimed |
| EP-0759298-A2 | Pyrazolopyrimidine derivates as antihypertensive agents | Maeda, Hiroshi, Dr. (JP) | 1997-02-26 | — | — | EP | claimed |
| EP-0515379-A4 | ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES | GLYCOMED INC (US) | 1994-09-14 | — | — | EP | claimed |
| EP-0515379-A1 | ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES | GLYCOMED INCORPORATED (US) | 1992-12-02 | — | — | EP | claimed |
| US-5094740-A | TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES | GLYCOMED, INC. (US) | 1992-03-10 | — | — | US | claimed |
| WO-1991012275-A1 | TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES | GLYCOMED INCORPORATED (US) | 1991-08-22 | — | — | WO | claimed |
| WO-1991012276-A1 | ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES | GLYCOMED INCORPORATED (US) | 1991-08-22 | — | — | WO | claimed |